Pre-seed open · 12 months to first market AVIX Pharmaceuticals Limited · United Kingdom & Bangladesh
SCIENTIFIC ADVISOR PROFILE · DR DAVID BROWN

Drug discovery experience.
Applied with discipline.

Across more than 50 years in global pharmaceutical R&D, biotechnology and company building, Dr David Brown has helped move medicines from discovery towards clinical proof. Since 2022, he has brought that judgement to AVIX as an independent scientific advisor focused on T-Booster and Green Antibiotics. AVIX Water is outside his advisory remit.

Advisory journey from global pharmaceutical research through biotechnology to AVIX, T-Booster and Green Antibiotics
50+ yearsPharmaceutical R&D
ViagraCo-inventor
2,000+Scientists led
Since 2022AVIX scientific adviser
Dr David Brown

Dr David Brown

Independent Scientific Advisor · AVIX Pharmaceuticals
Pharma career
ICI/Zeneca · Pfizer · Glaxo Wellcome · Roche
Biotech leadership
Cellzome · Crescendo Biologics · Healx
Fellowships
Royal Society of Medicine · Royal Society of Chemistry
Based
Cambridge · United Kingdom
LinkedIn profile ↗
01 ·Experience brought to AVIX

Drug-discovery judgement built at global scale.

Dr David Brown brings more than 50 years of experience across pharmaceutical research, biotechnology and company building. His career includes senior work with ICI Pharmaceuticals/Zeneca, Pfizer, Glaxo Wellcome and Hoffmann-La Roche, followed by biotechnology leadership including President and Chief Executive of Cellzome AG.

At Pfizer, he was named a co-inventor on the patent for Viagra and led the programme from early research through proof of clinical efficacy in human trials. He also played a pivotal role in the discovery of Relpax, a treatment for migraine.

At Roche in Switzerland, he served as a director overseeing approximately 2,000 staff working in drug discovery across research sites in the United States, Europe and Asia. He later helped found biotechnology ventures including Crescendo Biologics and Healx — experience that gives him an unusually broad view of how scientific ideas succeed, fail and mature.

PfizerViagra programme leadershipRelpaxMigraine drug discoveryRocheGlobal discovery leadershipBiotechCellzome · Crescendo · Healx
02 ·Green Antibiotics

Drug-discovery discipline applied to antimicrobial resistance.

Dr Brown works with Dr Sheikh to pressure-test the programme's scientific logic, guide development thinking and keep a credible route from screening and in-vitro evidence towards controlled animal validation and partnership.

01 · Question

Scientific rationale

  • Separate hypotheses from evidence
  • Test what the result truly proves
  • Keep claims proportionate
02 · Develop

Development strategy

  • Prioritise microbiology and safety
  • Keep formulation questions explicit
  • Sequence validation intelligently
03 · Interpret

Evidence quality

  • Use meaningful comparators
  • Separate signal from proof
  • Keep uncertainty visible
04 · Advance

Translation pathway

  • Support decision-grade validation
  • Align positioning with evidence
  • Advance only when data supports it
03 ·AMR perspective

Experience beyond one programme.

Dr Brown brings external scrutiny from UK AMR work and global-health drug development, helping Green Antibiotics stay scientifically disciplined and translation-focused.

AMR perspectiveIndependent scrutiny

Antibiotic Research UK

  • Chaired the Science Committee
  • Worked with UK AMR experts
  • Added independent scientific scrutiny
Global healthTranslation

OneWorld Health / PATH

  • Contributed to global-health drug development
  • Co-invented iOWH-032 for enteric disease
  • Helped progress the programme through Phase 1
AVIX collaborationCurrent

Green Antibiotics

  • Advises on scientific priorities
  • Challenges evidence and development logic
  • Helps shape a credible translation path
Visit Green Antibiotics science ↗
04 ·Independent AVIX role

Independent judgement. Long-term involvement.

Since 2022, Dr Brown has advised AVIX Pharmaceuticals in the UK, working closely with Dr Sheikh across science, development thinking and commercial readiness. The value of the relationship is independence as much as experience: he provides challenge at decisions that affect scientific credibility.

Within Green Antibiotics, that means helping the programme move from laboratory evidence towards the next validation gates without allowing the commercial narrative to outrun the science.

Since 2022AVIX advisory relationship
50+ yrsDrug discovery & pharma
GAAMR collaboration
IndependentScientific judgement
Scientific collaboration

Move the programme through the next evidence gates.

Discuss scientific collaboration, validation, investment or commercial partnership.